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Literature summary for 5.1.3.2 extracted from

  • Alphey, M.S.; Burton, A.; Urbaniak, M.D.; Boons, G.J.; Ferguson, M.A.; Hunter, W.N.
    Trypanosoma brucei UDP-galactose-4-epimerase in ternary complex with NAD+ and the substrate analog UDP-4-deoxy-4-fluoro-alpha -D-galactose (2006), Acta Crystallogr. Sect. F, F62, 829-834.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.1.3.2

Activating Compound

Activating Compound Comment Organism Structure
NADH
-
 Trypanosoma brucei
NADPH
-
 Trypanosoma brucei

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop method Trypanosoma brucei

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei
-
-
-

Subunits

Subunits Comment Organism
dimer The resulting model is composed of four subunits forming two physiological dimers (subunits AB and CD). Subunit A comprises residues -1–150, 157–237 and 249–381, subunit B residues -1–150, 158–235 and 249–381, subunit C residues -1–152, 158–237 and 248–381 and subunit D residues -1–150, 157–235 and 249–381.The -1 refers to a serine residue which precedes the initiating methionine and is an artifact of the expression plasmid that generates an N-terminal extension. There are several missing residues which belong to flexible surface loops. Each active site is occupied by well ordered NAD+ and UDP-FGal. Trypanosoma brucei

Synonyms

Synonyms Comment Organism
GalE
-
 Trypanosoma brucei
UDP-galactose-4'-epimerase
-
 Trypanosoma brucei