Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.1.1.22 extracted from

  • Zhao, S.; Kumar, R.; Sakai, A.; Vetting, M.W.; Wood, B.M.; Brown, S.; Bonanno, J.B.; Hillerich, B.S.; Seidel, R.D.; Babbitt, P.C.; Almo, S.C.; Sweedler, J.V.; Gerlt, J.A.; Cronan, J.E.; Jacobson, M.P.
    Discovery of new enzymes and metabolic pathways by using structure and genome context (2013), Nature, 502, 698-702.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.1.1.22

Cloned(Commentary)

Cloned (Comment) Organism
-
 Salipiger bermudensis

Crystallization (Commentary)

Crystallization (Comment) Organism
structure of apo protein and modeling of ligands Salipiger bermudensis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
8
-
 L-proline betaine pH not specified in the publication, temperature not specified in the publication Salipiger bermudensis
42
-
 trans-4-hydroxy-L-proline betaine pH not specified in the publication, temperature not specified in the publication Salipiger bermudensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-proline betaine Salipiger bermudensis
-
 D-proline betaine
-
 ?
L-proline betaine Salipiger bermudensis JCM 13377
-
 D-proline betaine
-
 ?
additional information Salipiger bermudensis the enzyme catalyzes 2-epimerization of trans-4-hydroxy-L-proline betaine and cis-4-hydroxy-D-proline betaine ?
-
 ?
additional information Salipiger bermudensis JCM 13377 the enzyme catalyzes 2-epimerization of trans-4-hydroxy-L-proline betaine and cis-4-hydroxy-D-proline betaine ?
-
 ?
trans-4-hydroxy-L-proline betaine Salipiger bermudensis
-
 cis-4-hydroxy-D-proline betaine
-
 ?
trans-4-hydroxy-L-proline betaine Salipiger bermudensis JCM 13377
-
 cis-4-hydroxy-D-proline betaine
-
 ?

Organism

Organism UniProt Comment Textmining
Salipiger bermudensis Q0FPQ4
-
-
Salipiger bermudensis JCM 13377 Q0FPQ4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-proline betaine
-
 Salipiger bermudensis D-proline betaine
-
 ?
L-proline betaine
-
 Salipiger bermudensis JCM 13377 D-proline betaine
-
 ?
additional information the enzyme catalyzes 2-epimerization of trans-4-hydroxy-L-proline betaine and cis-4-hydroxy-D-proline betaine Salipiger bermudensis ?
-
 ?
additional information the enzyme catalyzes 2-epimerization of trans-4-hydroxy-L-proline betaine and cis-4-hydroxy-D-proline betaine Salipiger bermudensis JCM 13377 ?
-
 ?
trans-4-hydroxy-L-proline betaine
-
 Salipiger bermudensis cis-4-hydroxy-D-proline betaine
-
 ?
trans-4-hydroxy-L-proline betaine
-
 Salipiger bermudensis JCM 13377 cis-4-hydroxy-D-proline betaine
-
 ?

Synonyms

Synonyms Comment Organism
hpbD
-
 Salipiger bermudensis

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
5.3
-
 L-proline betaine pH not specified in the publication, temperature not specified in the publication Salipiger bermudensis
330
-
 trans-4-hydroxy-L-proline betaine pH not specified in the publication, temperature not specified in the publication Salipiger bermudensis

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.7
-
 L-proline betaine pH not specified in the publication, temperature not specified in the publication Salipiger bermudensis
7.8
-
 trans-4-hydroxy-L-proline betaine pH not specified in the publication, temperature not specified in the publication Salipiger bermudensis