Application | Comment | Organism |
---|---|---|
biotechnology | The results indicate that Penecillium chrysogenum can be used as heterologous host for the production of deacetylcephalosporin C | Acremonium chrysogenum |
Cloned (Comment) | Organism |
---|---|
Penecillium chrysogenum strains are constructed expressing cefD1 (isopenecillin N-CoA synthetase), cefD2 (isopenecillin N-CoA epimerase), cefEF (deacetylcephalosporin-actyltransferase), and cefG (deacetylcephalosporin C synthetase) genes cloned from Acremonium chrysogenum. HPLC analysis of cell extracts show that transformant TA64, TA71, and TA98 accumulate intracellularly deacetylcephalosporin C and, in the last strain (TA98), also cephalosporin C. | Acremonium chrysogenum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acremonium chrysogenum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isopenicillin N | - |
Acremonium chrysogenum | penicillin N | - |
? |
Synonyms | Comment | Organism |
---|---|---|
isopenecillin N-CoA epimerase | - |
Acremonium chrysogenum |
isopenicillin N epimerase | - |
Acremonium chrysogenum |