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Literature summary for 5.1.1.1 extracted from

  • Walsh, C.T.
    Enzymes in the D-alanine branch of bacterial cell wall peptidoglycan assembly (1989), J. Biol. Chem., 264, 2393-2396.
    View publication on PubMed
Search for more literature for 5.1.1.1

Protein Variants

Protein Variants Comment Organism
additional information
-
 Geobacillus stearothermophilus
additional information double mutant for the alr encoded enzyme and the dad B encoded enzyme display a phenotype of requirement for exogenous D-Ala for growth Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Salmonella enterica subsp. enterica serovar Typhimurium alr racemase is constitutive and serves an anabolic function, dadB encoded enzyme is inducible and required for cell growth on L-Ala ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Geobacillus stearothermophilus
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
 encoded by alr and dadB gene
-
Staphylococcus sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala
-
 Salmonella enterica subsp. enterica serovar Typhimurium D-Ala
-
 ?
L-Ala
-
 Escherichia coli D-Ala
-
 ?
L-Ala
-
 Geobacillus stearothermophilus D-Ala
-
 ?
L-Ala
-
 Staphylococcus sp. D-Ala
-
 ?
additional information alr racemase is constitutive and serves an anabolic function, dadB encoded enzyme is inducible and required for cell growth on L-Ala Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?

Subunits

Subunits Comment Organism
dimer
-
 Geobacillus stearothermophilus
monomer
-
 Salmonella enterica subsp. enterica serovar Typhimurium