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Literature summary for 5.1.1.1 extracted from

  • Fenn, T.D.; Stamper, G.F.; Morollo, A.A.; Ringe, D.
    A side reaction of alanine racemase: transamination of cycloserine (2003), Biochemistry, 42, 5775-5783.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop method using purified enzyme concentrated to 22 mg/ml. The hanging drop contains 0.01 ml of the protein solution, 0.01 ml of 23% polyethylene glycol 4K, 200 mM sodium acetate and 100 mM Tris, pH 8.5. Drops are equilibrated against 0.7 ml of polyethylene glycol 4K solution Geobacillus stearothermophilus

Inhibitors

Inhibitors Comment Organism Structure
cycloserine suicide inhibitor Geobacillus stearothermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Ala Geobacillus stearothermophilus the enzyme catalyzes the first committed step in bacterial cell wall biosynthesis D-Ala
-
?

Organism

Organism UniProt Comment Textmining
Geobacillus stearothermophilus P10724
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala the enzyme catalyzes the first committed step in bacterial cell wall biosynthesis Geobacillus stearothermophilus D-Ala
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?