Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NO | interacts with the heme cofactor via the heme NO oxygen domain, structural basis, thermodynamics, and kinetics, activation mechanism involving the alphaFbeta1 loop in the iron proximal histidine bond breaking process, overview | Caldanaerobacter subterraneus subsp. tengcongensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | Caldanaerobacter subterraneus subsp. tengcongensis | soluble guanylate cyclase is the mammalian receptor for nitric oxide | 3',5'-cyclic GMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caldanaerobacter subterraneus subsp. tengcongensis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | - |
Caldanaerobacter subterraneus subsp. tengcongensis | 3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | soluble guanylate cyclase is the mammalian receptor for nitric oxide | Caldanaerobacter subterraneus subsp. tengcongensis | 3',5'-cyclic GMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sGC | - |
Caldanaerobacter subterraneus subsp. tengcongensis |
soluble guanylate cyclase | - |
Caldanaerobacter subterraneus subsp. tengcongensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Caldanaerobacter subterraneus subsp. tengcongensis |