Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.6.1.2 extracted from

  • Capece, L.; Estrin, D.A.; Marti, M.A.
    Dynamical characterization of the heme NO oxygen binding (HNOX) domain. Insight into soluble guanylate cyclase allosteric transition (2008), Biochemistry, 47, 9416-9427.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
NO interacts with the heme cofactor via the heme NO oxygen domain, structural basis, thermodynamics, and kinetics, activation mechanism involving the alphaFbeta1 loop in the iron proximal histidine bond breaking process, overview Caldanaerobacter subterraneus subsp. tengcongensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Caldanaerobacter subterraneus subsp. tengcongensis soluble guanylate cyclase is the mammalian receptor for nitric oxide 3',5'-cyclic GMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Caldanaerobacter subterraneus subsp. tengcongensis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
Caldanaerobacter subterraneus subsp. tengcongensis 3',5'-cyclic GMP + diphosphate
-
?
GTP soluble guanylate cyclase is the mammalian receptor for nitric oxide Caldanaerobacter subterraneus subsp. tengcongensis 3',5'-cyclic GMP + diphosphate
-
?

Synonyms

Synonyms Comment Organism
sGC
-
Caldanaerobacter subterraneus subsp. tengcongensis
soluble guanylate cyclase
-
Caldanaerobacter subterraneus subsp. tengcongensis

Cofactor

Cofactor Comment Organism Structure
heme
-
Caldanaerobacter subterraneus subsp. tengcongensis