Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5(4-morpholinyl)-4,6-pyrimidinediamine | trivial name BAY 41-8543, 66fold activation at 0.1 mM, strong synergistic activation in the presence of NO | Homo sapiens | |
4-[((4-carboxybutyl){2-[(4-phenethylbenzol)oxy]phenethyl}amino)methyl] benzoic acid | trivial name BAY 58-2667, heme-independent activator, 30fold activation at 0.01 mM | Homo sapiens | |
NO | - |
Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression in Sf9 insect cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1H-(1,2,4)-oxadiazole-(4,3-a)quinoxalin-1-one | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.074 | - |
GTP | at the basal state of sGC | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | Homo sapiens | - |
3',5'-cyclic GMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | - |
Homo sapiens | 3',5'-cyclic GMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
soluble guanylyl cyclase | - |
Homo sapiens |