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Literature summary for 4.6.1.2 extracted from

  • Nagao,S.; Nozawa, Y.
    Properties of digitonin-solubilized calmodulin-dependent guanylate cyclase from the plasma membranes of Tetrahymena pyriformis NT-1 cells (1987), Arch. Biochem. Biophys., 252, 179-187.
    View publication on PubMed
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General Stability

General Stability Organism
glycerol stabilizes Tetrahymena pyriformis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.03
-
 GTP
-
 Tetrahymena pyriformis
0.14
-
 GTP
-
 Tetrahymena pyriformis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic membrane
-
 Tetrahymena pyriformis
-
-
particle-bound
-
 Tetrahymena pyriformis
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Tetrahymena pyriformis
Mn2+
-
 Tetrahymena pyriformis

Organism

Organism UniProt Comment Textmining
Tetrahymena pyriformis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Tetrahymena pyriformis

Source Tissue

Source Tissue Comment Organism Textmining

Storage Stability

Storage Stability Organism
-20°C, 1 week Tetrahymena pyriformis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP GTP in form of MgGTP2- Tetrahymena pyriformis 3',5'-cyclic GMP + diphosphate
-
 ?
GTP GTP in form of MnGTP2- Tetrahymena pyriformis 3',5'-cyclic GMP + diphosphate
-
 ?

Cofactor

Cofactor Comment Organism Structure
Calmodulin activation in presence of Ca2+ Tetrahymena pyriformis