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Literature summary for 4.6.1.16 extracted from

  • Di Nicola Negri, E.; Fabbri, S.; Bufardeci, E.; Baldi, M.I.; Gandini Attardi, D.; Mattoccia, E.; Tocchini-Valentini, G.P.
    The eucaryal tRNA splicing endonuclease recognizes a tripartite set of RNA elements (1997), Cell, 89, 859-866.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Xenopus laevis
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Reaction

Reaction Comment Organism Reaction ID
pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus mechanism of substrate recognition Xenopus laevis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme contains two functionally independent active sites for 5’ and 3’ splicing Xenopus laevis ?
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?
tRNA precursor
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Xenopus laevis a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
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?