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Literature summary for 4.6.1.16 extracted from

  • Miao, F.; Abelson, J.
    Yeast tRNA-splicing endonuclease cleaves precursor tRNA in a random pathway (1993), J. Biol. Chem., 268, 672-677.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tRNA precursor Saccharomyces cerevisiae
-
a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?
tRNA precursor Saccharomyces cerevisiae 20B-12-1
-
a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae 20B-12-1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tRNA precursor
-
Saccharomyces cerevisiae a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?
tRNA precursor cleaves pre-tRNA in a random order creating two routes for removal of the introns from pre-tRNA Saccharomyces cerevisiae a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?
tRNA precursor cleaves both 3'- and 5'-nicked pre-tRNAPhe Saccharomyces cerevisiae a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?
tRNA precursor
-
Saccharomyces cerevisiae 20B-12-1 a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?
tRNA precursor cleaves pre-tRNA in a random order creating two routes for removal of the introns from pre-tRNA Saccharomyces cerevisiae 20B-12-1 a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?
tRNA precursor cleaves both 3'- and 5'-nicked pre-tRNAPhe Saccharomyces cerevisiae 20B-12-1 a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
?