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Literature summary for 4.6.1.1 extracted from

  • Heindorff, K.; Blenau, W.; Walz, B.; Baumann, O.
    Characterization of a Ca2+/calmodulin-dependent AC1 adenylyl cyclase in a non-neuronal tissue, the blowfly salivary gland (2012), Cell Calcium, 52, 103-112.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Calmodulin co-application of 200 nM Ca2+ and calmodulin enhances the rate of cAMP synthesis by a factor of about 2.5 Calliphora vicina

Cloned(Commentary)

Cloned (Comment) Organism
-
Calliphora vicina

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Calliphora vicina 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Calliphora vicina

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Calliphora vicina
-
3',5'-cyclic AMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Calliphora vicina
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
salivary gland
-
Calliphora vicina
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
Calliphora vicina 3',5'-cyclic AMP + diphosphate
-
?

Synonyms

Synonyms Comment Organism
adenylyl cyclase
-
Calliphora vicina

General Information

General Information Comment Organism
physiological function the Ca2+/calmodulin-dependent enzyme serves as a link between the inositol 1,4,5-trisphosphate/Ca2+ and the cAMP/protein kinase A signalling pathways in the salivary gland of the blowfly and is important for the amplification and optimization of the secretory response Calliphora vicina