Protein Variants | Comment | Organism |
---|---|---|
additional information | sperm from Sacy null mice are immotile or weakly motile, but their motility is activated by the cAMP analogues N6,2'-O-dibutyryladenosine 3',5'-cyclic monophosphate and adenosine 3',5'-cyclic monophosphate acetoxymethyl ester activated motility. Ca2+ cannot substitute for cAMP analogues in activating motility in the mutant, overview | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | stimulates the soluble adenylyl cyclase | Mus musculus | |
HCO3- | stimulates the soluble adenylyl cyclase | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | Mus musculus | - |
3',5'-cyclic-AMP + diphosphate | - |
? | |
additional information | Mus musculus | soluble adenylyl cyclase is an essential component of cAMP-signalling cascades that activate sperm motility and capacitate sperm, but soluble adenylyl cyclase does not have a direct effect on hyperactivation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8C0T9 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
sperm | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Mus musculus | 3',5'-cyclic-AMP + diphosphate | - |
? | |
additional information | soluble adenylyl cyclase is an essential component of cAMP-signalling cascades that activate sperm motility and capacitate sperm, but soluble adenylyl cyclase does not have a direct effect on hyperactivation | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SACY | - |
Mus musculus |
soluble adenylyl cyclase | - |
Mus musculus |