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Literature summary for 4.6.1.1 extracted from

  • Cohen, R.J.; Ness, J.L.; Whiddon, S.M.
    Adenylate cyclase from Phycomyces sporangiophore (1980), Phytochemistry, 19, 1913-1918.
No PubMed abstract available
Search for more literature for 4.6.1.1

Activating Compound

Activating Compound Comment Organism Structure
catecholamine activation Phycomyces blakesleeanus
dopamine activation Phycomyces blakesleeanus
epinephrin activation Phycomyces blakesleeanus
GTP activation Phycomyces blakesleeanus

Inhibitors

Inhibitors Comment Organism Structure
alloxan
-
 Phycomyces blakesleeanus
ATP high concentrations Phycomyces blakesleeanus
Ca2+
-
 Phycomyces blakesleeanus
Mn2+
-
 Phycomyces blakesleeanus
NaF
-
 Phycomyces blakesleeanus
nucleotides
-
 Phycomyces blakesleeanus
Ouabain
-
 Phycomyces blakesleeanus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.5
-
 ATP
-
 Phycomyces blakesleeanus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Phycomyces blakesleeanus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
F-
-
 Phycomyces blakesleeanus
Mg2+
-
 Phycomyces blakesleeanus

Organism

Organism UniProt Comment Textmining
Phycomyces blakesleeanus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sporangiophore
-
 Phycomyces blakesleeanus
-

Storage Stability

Storage Stability Organism
-20°C, 3 weeks Phycomyces blakesleeanus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Phycomyces blakesleeanus 3',5'-cyclic AMP + diphosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8.2
-
 Phycomyces blakesleeanus

Cofactor

Cofactor Comment Organism Structure
ADP activation Phycomyces blakesleeanus
AMP activation Phycomyces blakesleeanus
IMP activation Phycomyces blakesleeanus