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Literature summary for 4.4.1.5 extracted from
- Highlights and hotspots of protein glycation in end-stage renal disease (2009), Semin. Dial., 22, 400-404.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| methylglyoxal + glutathione | Homo sapiens | - |
(R)-S-lactoylglutathione | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| methylglyoxal + glutathione | - |
Homo sapiens | (R)-S-lactoylglutathione | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glyoxalase I | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | - |
Homo sapiens | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | activation of receptor for advanced glycation endproducts by S100A12 protein decreases the expression of glyoxalase 1 | down |
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Release 2023.1 (January 2023)
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