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Literature summary for 4.4.1.5 extracted from
- Glyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxification (2009), PLoS ONE, 4, e6805.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| kinetoplast | - |
Leishmania donovani | 20023 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 16000 | - |
native enzyme, SDS-PAGE | Leishmania donovani |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania donovani | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| promastigote | - |
Leishmania donovani | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| methylglyoxal + glutathione | - |
Leishmania donovani | (R)-S-lactoylglutathione | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GloI | - |
Leishmania donovani |
| glyoxalase I | - |
Leishmania donovani |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | - |
Leishmania donovani | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | GLO I heterozygous mutants exhibit reduced methylglyoxal detoxification | Leishmania donovani |
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Release 2023.1 (January 2023)
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