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Literature summary for 4.4.1.5 extracted from
- Purification, characterization and kinetic studies of glyoxalase I from rat liver (1979), Biochim. Biophys. Acta, 566, 362-370.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| amino-group reagents | - |
Rattus norvegicus | |
| GSH | competitive; non-linear inhibition | Rattus norvegicus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | activates apoenzyme | Rattus norvegicus | |
| Mg2+ | activates apoenzyme | Rattus norvegicus | |
| Mn2+ | activates apoenzyme | Rattus norvegicus | |
| Ni2+ | activates apoenzyme | Rattus norvegicus | |
| Zn2+ | zinc metalloenzymes | Rattus norvegicus | |
| Zn2+ | apoenzyme is catalytically inactive, but is partially restored by Zn2+ | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 27000 | - |
2 * 27000, SDS-PAGE | Rattus norvegicus |
| 54000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rattus norvegicus |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 27000, SDS-PAGE | Rattus norvegicus |
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