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Literature summary for 4.4.1.5 extracted from

  • Murata, K.; Saikusa, T.; Watanabe, K.; Inoue, Y.; Fukuda, Y.; Shimosaka, M.; Kimura, A.
    Complete purification of yeast glyoxalase I and its activation by ferrous ions and polyamines (1986), Agric. Biol. Chem., 50, 2381-2383.
No PubMed abstract available
Search for more literature for 4.4.1.5

Activating Compound

Activating Compound Comment Organism Structure
polyamines activate Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ restores activity after EDTA treatment Saccharomyces cerevisiae
Fe2+ activates Saccharomyces cerevisiae
Mg2+ restores activity after EDTA treatment Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
 gel giltration Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutathione + methylglyoxal Saccharomyces cerevisiae detoxification of methylglyoxal ?
-
 ?
glutathione + methylglyoxal Saccharomyces cerevisiae DKD-5D-H detoxification of methylglyoxal ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 DKD-5D-H
-
Saccharomyces cerevisiae DKD-5D-H
-
 DKD-5D-H
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
963
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + methylglyoxal
-
 Saccharomyces cerevisiae S-lactoylglutathione
-
 ?
glutathione + methylglyoxal
-
 Saccharomyces cerevisiae DKD-5D-H S-lactoylglutathione
-
 ?
glutathione + methylglyoxal detoxification of methylglyoxal Saccharomyces cerevisiae ?
-
 ?
glutathione + methylglyoxal detoxification of methylglyoxal Saccharomyces cerevisiae DKD-5D-H ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 33000, SDS-PAGE Saccharomyces cerevisiae