Literature summary for 4.4.1.22 extracted from

Neculai, A.M.; Neculai, D.; Griesinger, C.; Vorholt, J.A.; Becker, S.
A dynamic zinc redox switch (2005), J. Biol. Chem., 280, 2826-2830.

Search for more literature for 4.4.1.22

Crystallization (Commentary)

Crystallization (Comment)	Organism
vapor diffusion method, crystallization of enzyme and enzyme in complex with glutathione	Paracoccus denitrificans

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn	the enzyme has a new fold with two zinc-sulfur centers, one that is structural (zinc tetracoordinated) and one catalytic (zinc apparently tricoordinated). In the complex of enzyme with glutathione, the catalytic zinc is displaced due to disulfide bond formation of glutathione with one of the zinc-coordinating cysteines	Paracoccus denitrificans

Organism

Organism	UniProt	Comment	Textmining
Paracoccus denitrificans	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Paracoccus denitrificans

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
glutathione + formaldehyde	-	Paracoccus denitrificans	S-(hydroxymethyl)glutathione	-	?

Synonyms

Synonyms	Comment	Organism
Gfa	-	Paracoccus denitrificans

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Release 2023.1 (January 2023)