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Literature summary for 4.4.1.21 extracted from
- AI-3 synthesis is not dependent on luxS in Escherichia coli (2006), J. Bacteriol., 188, 5668-5681.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | autoinducer-2 promotes interspecies signaling, the autoinducer-3 activates enterohemorrhagic Escherichia coli virulence genes, knocking out luxS in the enterohemorrhagic human pathogen Escherichia coli reveals a defect in AI-3 production, but not in AI-2 production | Escherichia coli |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| as lsrR knockout by chromosomal gene replacement | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | Q8X902 | EHEC, O157:H7 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-(5-deoxy-D-ribos-5-yl)-L-homocysteine | - |
Escherichia coli | L-homocysteine + (S)-4,5-dihydroxypentan-2,3-dione | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| lsrR | - |
Escherichia coli |
| LuxS | - |
Escherichia coli |
| S-ribosylhomocysteinase | - |
Escherichia coli |
| S-ribosylhomocysteine lyase | - |
Escherichia coli |
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