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Literature summary for 4.4.1.13 extracted from

  • Gul Altuntas, T.; Kharasch, E.D.
    Biotransformation of L-cysteine S-conjugates and N-acetyl-L-cysteine S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in human kidney in vitro: interindividual variability in N-acetylation, N-deacetylation, and beta-lyase-catalyzed metabolism (2002), Drug Metab. Dispos., 30, 148-154.
    View publication on PubMed
Search for more literature for 4.4.1.13

Application

Application Comment Organism
medicine considerable interindividual variability in enzyme catalyzed step of degradation of the anesthetic sevoflurane Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
microsome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-[2-(fluoromethoxy)-1,1,3,3,3-pentafluoropropyl]-L-cysteine
-
 Homo sapiens pyruvate + ?
-
 ?
S-[2-(fluoromethoxy)-1,3,3,3-tetrafluoropropyl]-L-cysteine
-
 Homo sapiens pyruvate + ?
-
 ?