General Stability | Organism |
---|---|
pyridoxal 5'-phosphate stabilizes | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-hydroxykynurenine | cysteine conjugate beta-lyase activity | Rattus norvegicus | |
hydroxylamine | - |
Rattus norvegicus | |
KCN | - |
Rattus norvegicus | |
kynurenine | cysteine conjugate beta-lyase activity | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.013 | - |
3-hydroxy-kynurenine | - |
Rattus norvegicus | |
0.4 | - |
kynurenine | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
2 * 55000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0817 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxykynurenine | - |
Rattus norvegicus | ? | - |
? | |
kynurenine | - |
Rattus norvegicus | ? | - |
? | |
xenobiotics | - |
Rattus norvegicus | thiol + pyruvate + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 55000, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
More | rat liver enzyme: same enzyme as kynureninase | Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
70 | - |
50% loss of activity after 10 min | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Rattus norvegicus |