Literature summary for 4.4.1.11 extracted from

Palwai, N.R.; Zang, X.P.; Harrison, R.G.; Benbrook, D.; Pento, J.T.
Selective growth inhibition of cancer cells by L-methioninase-containing fusion protein targeted to the urokinase receptor (2009), Pharmacology, 84, 271-275.

Search for more literature for 4.4.1.11

Application

Application	Comment	Organism
medicine	inhibitory effect of fusion protein on an ovaran cancer cell line, fusion protein produces a dose-dependent inhibition of the proliferation of pancreatic cancer cell lines	Escherichia coli BL21

Protein Variants

Protein Variants	Comment	Organism
additional information	fusion protein consisting of an amino-terminal fragment of urokinase linked to the amino terminus of the enzyme, greater inhibitory effect on proliferation of cancer cell lines	Escherichia coli BL21
Y114F	reduced enzyme activity	Escherichia coli BL21

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli BL21	-	-	-

Synonyms

Synonyms	Comment	Organism
L-methionase	-	Escherichia coli BL21

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Release 2023.1 (January 2023)