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Literature summary for 4.4.1.11 extracted from

  • Rebeille, F.; Jabrin, S.; Bligny, R.; Loizeau, K.; Gambonnet, B.; Van Wilder, V.; Douce, R.; Ravanel, S.
    Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses (2006), Proc. Natl. Acad. Sci. USA, 103, 15687-15692.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.4.1.11

Cloned(Commentary)

Cloned (Comment) Organism
-
 Arabidopsis thaliana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
10.6
-
 L-methionine pH 7.2, 30°C Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Arabidopsis thaliana 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47820
-
 x * 47820, calculated, x * 48000, SDS-PAGE Arabidopsis thaliana
48000
-
 x * 47820, calculated, x * 48000, SDS-PAGE Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-methionine + H2O Arabidopsis thaliana
-
 methanethiol + NH3 + 2-oxobutanoate part of the methanethiol produced can react with an activated form of serine to produce S-methylcysteine. Product 2-oxobutanoate enters the papthway of Ile synthesis in plastids ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 expression of enzyme is induced in response to high methionine levels
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information sequence contains no targeting signal Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-methionine + H2O
-
 Arabidopsis thaliana methanethiol + NH3 + 2-oxobutanoate part of the methanethiol produced can react with an activated form of serine to produce S-methylcysteine. Product 2-oxobutanoate enters the papthway of Ile synthesis in plastids ?
L-methionine + H2O
-
 Arabidopsis thaliana methanethiol + NH3 + 2-oxobutanoate part of the methanethiol produced can react with an activated form of serine to produce S-methylcysteine ?

Subunits

Subunits Comment Organism
? x * 47820, calculated, x * 48000, SDS-PAGE Arabidopsis thaliana