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Literature summary for 4.4.1.1 extracted from

  • Yoshida, Y.; Negishi, M.; Amano, A.; Oho, T.; Nakano, Y.
    Differences in the betaC-S lyase activities of viridans group streptococci (2002), Biochem. Biophys. Res. Commun., 300, 55-60.
    View publication on PubMed

Application

Application Comment Organism
medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus mutans
medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus salivarius
medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus oralis
medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus sobrinus
medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus gordonii
medicine enzyme participates in hydrogen sulfide production in the oral cavity Streptococcus anginosus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.68
-
L-cysteine pH 7.6, 37°C Streptococcus gordonii
0.75
-
L-cysteine pH 7.6, 37°C Streptococcus sobrinus
0.88
-
L-cysteine pH 7.6, 37°C Streptococcus anginosus
1.08
-
L-cysteine pH 7.6, 37°C Streptococcus oralis
1.16
-
L-cysteine pH 7.6, 37°C Streptococcus salivarius
2.46
-
L-cysteine pH 7.6, 37°C Streptococcus mutans
8.7
-
L-cystathionine pH 7.6, 37°C Streptococcus gordonii
10.6
-
L-cystathionine pH 7.6, 37°C Streptococcus sobrinus
11.1
-
L-cystathionine pH 7.6, 37°C Streptococcus anginosus
11.2
-
L-cystathionine pH 7.6, 37°C Streptococcus oralis
11.8
-
L-cystathionine pH 7.6, 37°C Streptococcus mutans
25.5
-
L-cystathionine pH 7.6, 37°C Streptococcus salivarius

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44000
-
x * 44000, SDS-PAGE Streptococcus mutans
44000
-
x * 44000, SDS-PAGE Streptococcus salivarius
44000
-
x * 44000, SDS-PAGE Streptococcus oralis
44000
-
x * 44000, SDS-PAGE Streptococcus sobrinus
44000
-
x * 44000, SDS-PAGE Streptococcus gordonii
44000
-
x * 44000, SDS-PAGE Streptococcus anginosus

Organism

Organism UniProt Comment Textmining
Streptococcus anginosus
-
-
-
Streptococcus gordonii
-
-
-
Streptococcus mutans
-
-
-
Streptococcus oralis
-
-
-
Streptococcus salivarius
-
-
-
Streptococcus sobrinus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-cystathione + H2O
-
Streptococcus mutans L-cysteine + NH3 + 2-oxobutanoate
-
?
L-cystathione + H2O
-
Streptococcus salivarius L-cysteine + NH3 + 2-oxobutanoate
-
?
L-cystathione + H2O
-
Streptococcus oralis L-cysteine + NH3 + 2-oxobutanoate
-
?
L-cystathione + H2O
-
Streptococcus sobrinus L-cysteine + NH3 + 2-oxobutanoate
-
?
L-cystathione + H2O
-
Streptococcus gordonii L-cysteine + NH3 + 2-oxobutanoate
-
?
L-cystathione + H2O
-
Streptococcus anginosus L-cysteine + NH3 + 2-oxobutanoate
-
?
L-cystathionine + H2O
-
Streptococcus mutans L-cysteine + 2-oxobutanoate + NH3
-
?
L-cystathionine + H2O
-
Streptococcus salivarius L-cysteine + 2-oxobutanoate + NH3
-
?
L-cystathionine + H2O
-
Streptococcus oralis L-cysteine + 2-oxobutanoate + NH3
-
?
L-cystathionine + H2O
-
Streptococcus sobrinus L-cysteine + 2-oxobutanoate + NH3
-
?
L-cystathionine + H2O
-
Streptococcus gordonii L-cysteine + 2-oxobutanoate + NH3
-
?
L-cystathionine + H2O
-
Streptococcus anginosus L-cysteine + 2-oxobutanoate + NH3
-
?
L-cysteine + H2O
-
Streptococcus mutans sulfide + NH3 + pyruvate
-
?
L-cysteine + H2O
-
Streptococcus salivarius sulfide + NH3 + pyruvate
-
?
L-cysteine + H2O
-
Streptococcus oralis sulfide + NH3 + pyruvate
-
?
L-cysteine + H2O
-
Streptococcus sobrinus sulfide + NH3 + pyruvate
-
?
L-cysteine + H2O
-
Streptococcus gordonii sulfide + NH3 + pyruvate
-
?
L-cysteine + H2O
-
Streptococcus anginosus sulfide + NH3 + pyruvate
-
?

Subunits

Subunits Comment Organism
? x * 44000, SDS-PAGE Streptococcus mutans
? x * 44000, SDS-PAGE Streptococcus salivarius
? x * 44000, SDS-PAGE Streptococcus oralis
? x * 44000, SDS-PAGE Streptococcus sobrinus
? x * 44000, SDS-PAGE Streptococcus gordonii
? x * 44000, SDS-PAGE Streptococcus anginosus