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Literature summary for 4.3.1.24 extracted from
- Stabilization of phenylalanine ammonia lyase against organic solvent mediated deactivation (2007), Int. J. Pharm., 331, 107-115.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | use of enzyme in therapy of human phenylketonuria. Preparation of microcapsules containing emulsified enzyme. Emulsification of enzyme solution with water-saturated ether causes no loss in activity but results in loss of protein content in the aqueous phase due to specific loss of impurities in the protein sample. Emulsification of enzyme solution with ether/ethanol mixture results in a 50% decrase in activity. Hydroxypropyl-gamma-cyclodextrin and hydroxypropyl-beta-cyclodextrin protect against emulsion mediated loss in activity | Rhodotorula glutinis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhodotorula glutinis | - |
commercial product, 60% v/v solution in glycerol | - |
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Release 2023.1 (January 2023)
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