Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methoxamine | - |
Trypanosoma cruzi |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | of epimastigote, constitutively expressed | Trypanosoma cruzi | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | T1SGV2 | - |
- |
Trypanosoma cruzi | T1SHD4 | - |
- |
Trypanosoma cruzi Dm28c | T1SGV2 | - |
- |
Trypanosoma cruzi Dm28c | T1SHD4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
amastigote | enzyme is present and active in the two replicative parasite forms, epimastigotes and amastigotes, as well as in the nonreplicative, infective trypomastigotes | Trypanosoma cruzi | - |
epimastigote | enzyme is present and active in the two replicative parasite forms, epimastigotes and amastigotes, as well as in the nonreplicative, infective trypomastigotes | Trypanosoma cruzi | - |
trypomastigote | enzyme is present and active in the two replicative parasite forms, epimastigotes and amastigotes, as well as in the nonreplicative, infective trypomastigotes | Trypanosoma cruzi | - |
Synonyms | Comment | Organism |
---|---|---|
AP-endonuclease 1 | - |
Trypanosoma cruzi |
AP-endonuclease 2 | - |
Trypanosoma cruzi |
Ap1 | - |
Trypanosoma cruzi |
Ap2 | - |
Trypanosoma cruzi |
General Information | Comment | Organism |
---|---|---|
physiological function | overexpression of isoform AP1 increases epimastigotes viability when they are exposed to acute ROS/RNS attack. This protective effect is more evident when parasites are submitted to persistent reactive oxygen species/reactive nitrogen species exposition | Trypanosoma cruzi |