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Literature summary for 4.2.99.18 extracted from

  • Lingaraju, G.M.; Sartori, A.A.; Kostrewa, D.; Prota, A.E.; Jiricny, J.; Winkler, F.K.
    A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure (2005), Structure, 13, 87-98.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Pyrobaculum aerophilum

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the enzyme and that of its complex with 8-oxo-guanosine at 1.0 and 1.7 A resolution, respectively, are grown by sitting drops method Pyrobaculum aerophilum

Organism

Organism UniProt Comment Textmining
Pyrobaculum aerophilum Q8ZVK6
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-
Pyrobaculum aerophilum DSM 7523 Q8ZVK6
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-

Purification (Commentary)

Purification (Comment) Organism
-
Pyrobaculum aerophilum

Synonyms

Synonyms Comment Organism
archaeal GO glycosylase
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Pyrobaculum aerophilum
Pa-AGOG DNA glycosylase bifunctional enzyme that catalyzes the excision of 8-oxoguanine by cleaving the N-glycosylic bond between the base and the deoxyribose moiety (glycosylase activity) and subsequently cleave the DNA backbone (lyase activity) Pyrobaculum aerophilum