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Literature summary for 4.2.99.18 extracted from

  • Barraza-Salas, M.; Ibarra-Rodriguez, J.R.; Mellado, S.J.; Salas-Pacheco, J.M.; Setlow, P.; Pedraza-Reyes, M.
    Effects of forespore-specific overexpression of apurinic/apyrimidinic endonuclease Nfo on the DNA-damage resistance properties of Bacillus subtilis spores (2010), FEMS Microbiol. Lett., 302, 159-165.
    View publication on PubMed
Search for more literature for 4.2.99.18

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA Bacillus subtilis
-
 fragments of DNA
-
 ?
DNA Bacillus subtilis PS832
-
 fragments of DNA
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-
Bacillus subtilis PS832
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
spore
-
 Bacillus subtilis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA
-
 Bacillus subtilis fragments of DNA
-
 ?
DNA
-
 Bacillus subtilis PS832 fragments of DNA
-
 ?

Synonyms

Synonyms Comment Organism
AP endonuclease
-
 Bacillus subtilis
apurinic/apyrimidinic endonuclease
-
 Bacillus subtilis
Nfo
-
 Bacillus subtilis

General Information

General Information Comment Organism
physiological function overexpression of Nfo about 50fold in spores increases the wet heat resistance of exoA nfo Bacillus subtilis spores that lack most alpha/beta-type small, acid-soluble spore proteins, but has no effect on these spores' UV-C resistance. Nfo overexpression also increases these spores' dry heat resistance, and to levels slightly greater than that of wild type spores Bacillus subtilis