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Literature summary for 4.2.99.18 extracted from
- Regulatory roles of p21 and apurinic/apyrimidinic endonuclease 1 in base excision repair (2001), J. Biol. Chem., 276, 48781-48789.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA | Homo sapiens | - |
fragments of DNA | - |
? |  |
| additional information | Homo sapiens | enzyme stimulates long patch base excision repair by cleaving the DNA and then facilitating the sequential binding and catalysis by DNA polymerase beta, DNA polymerase delta, FEN1 and DNA ligase I | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA | - |
Homo sapiens | fragments of DNA | - |
? | |
| additional information | enzyme stimulates long patch base excision repair by cleaving the DNA and then facilitating the sequential binding and catalysis by DNA polymerase beta, DNA polymerase delta, FEN1 and DNA ligase I | Homo sapiens | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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