Literature summary for 4.2.3.81 extracted from

Landmann, C.; Fink, B.; Festner, M.; Dregus, M.; Engel, K.H.; Schwab, W.
Cloning and functional characterization of three terpene synthases from lavender (Lavandula angustifolia) (2007), Arch. Biochem. Biophys., 465, 417-429.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Lavandula angustifolia

General Stability

General Stability	Organism
bovine serum albumin stabilizes	Lavandula angustifolia

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0047	-	(2E,6E)-farnesyl diphosphate	pH 7.5, 23°C	Lavandula angustifolia

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	product formation is highest in the presence of the cofactor Mg2+ with product concentration peaking at 50 mM	Lavandula angustifolia
Mn2+	the assays with Mn2+ shows highest activity at 0.05 mM with 49% of the maximum product level	Lavandula angustifolia

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(2E,6E)-farnesyl diphosphate	Lavandula angustifolia	-	(-)-exo-alpha-bergamotene + diphosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Lavandula angustifolia	Q2XSC4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2E,6E)-farnesyl diphosphate	-	Lavandula angustifolia	(-)-exo-alpha-bergamotene + diphosphate	-	?

Synonyms

Synonyms	Comment	Organism
LaBERS	-	Lavandula angustifolia

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
23	-	assay at	Lavandula angustifolia
30	-	-	Lavandula angustifolia

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.033	-	(2E,6E)-farnesyl diphosphate	pH 7.5, 23°C	Lavandula angustifolia

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	assay at	Lavandula angustifolia
8	-	-	Lavandula angustifolia

kcat/KM [mM/s]

kcat/KM Value [1/mMs^-1]	kcat/KM Value Maximum [1/mMs^-1]	Substrate	Comment	Organism	Structure
0.7	-	(2E,6E)-farnesyl diphosphate	pH 7.5, 23°C	Lavandula angustifolia

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Release 2023.1 (January 2023)