Literature summary for 4.2.3.7 extracted from

Melillo, E.; Muntendam, R.; Quax, W.J.; Kayser, O.
Heterologous expression of pentalenene synthase (PSS) from Streptomyces UC5319 in Xanthophyllomyces dendrorhous (2012), J. Biotechnol., 161, 302-307.

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Application

Application	Comment	Organism
synthesis	production of pentalenene by expression of pentalenene synthase gene in Xanthophyllomyces dendrorhous with concurrent knock out of the native crtE or crtYB genes. Culturing the yeast in presence of dodecane traps the volatile compounds produced, and no other terpenoids are found as by products	Streptomyces exfoliatus

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Xanthophyllomyces dendrorhous	Streptomyces exfoliatus

Organism

Organism	UniProt	Comment	Textmining
Streptomyces exfoliatus	Q55012	-	-

Synonyms

Synonyms	Comment	Organism
PenA	-	Streptomyces exfoliatus

General Information

General Information	Comment	Organism
physiological function	expression in Xanthophyllomyces dendrorhous with concurrent knock out of the native crtE or crtYB genes. The transformations result in white colonies, showing a complete shutdown of the carotenoid production. All the mutant strains produce the sesquiterpene pentalenene and show no difference in growth when compared to the wild-type strain	Streptomyces exfoliatus

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Release 2023.1 (January 2023)