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Literature summary for 4.2.3.6 extracted from
- Fusarium graminearum gene deletion mutants map1 and tri5 reveal similarities and differences in the pathogenicity requirements to cause disease on Arabidopsis and wheat floral tissue (2008), New Phytol., 177, 990-1000.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| TRI5 gene is deleted using the split-marker technique, tri5 mutant shows reduced virulence when inoculated into wheat florets | Fusarium graminearum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| trans,trans-farnesyl diphosphate | Fusarium graminearum | the initial committing step into the trichothecene biosynthetic pathway, enzyme controls mycotoxin biosynthesis | trichodiene + diphosphate | - |
? |  |
| trans,trans-farnesyl diphosphate | Fusarium graminearum PH-1 | the initial committing step into the trichothecene biosynthetic pathway, enzyme controls mycotoxin biosynthesis | trichodiene + diphosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Fusarium graminearum | Q00909 | teleomorph Gibberella zeae | - |
| Fusarium graminearum PH-1 | Q00909 | teleomorph Gibberella zeae | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
both the wild-type PH-1 strain and the tri5 mutant exhibit full pathogenicity on Arabidopsis floral tissue | Fusarium graminearum |
| additional information | - |
tri5 mutants in strain PH-1 exhibit reduced virulence on wheat ears | Fusarium graminearum |
| additional information | - |
wild-type strain inoculations cause high levels of disease in both plant species and significant deoxynivalenol mycotoxin production. The tri5 mutant unable to produce deoxynivalenol mycotoxin exhibits reduced pathogenicity on wheat ears, causing only discrete eye-shaped lesions on spikelets which failed to infect the rachis. The tri5 mutant retains full pathogenicity on Arabidopsis floral tissue | Fusarium graminearum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| trans,trans-farnesyl diphosphate | the initial committing step into the trichothecene biosynthetic pathway, enzyme controls mycotoxin biosynthesis | Fusarium graminearum | trichodiene + diphosphate | - |
? | |
| trans,trans-farnesyl diphosphate | the initial committing step into the trichothecene biosynthetic pathway, enzyme controls mycotoxin biosynthesis | Fusarium graminearum PH-1 | trichodiene + diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| trichodiene synthase | - |
Fusarium graminearum |
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