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Literature summary for 4.2.3.6 extracted from

  • Cane, D.E.; Ha, H.J.
    Trichodiene biosynthesis and the enzymatic cyclization of nerolidyl pyrophosphate (1986), J. Am. Chem. Soc., 108, 3097-3099.
No PubMed abstract available
Search for more literature for 4.2.3.6

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(E,E)-farnesyl diphosphate Trichothecium roseum
-
 trichodiene + diphosphate
-
 ?
(E,E)-farnesyl diphosphate Fusarium sporotrichioides
-
 trichodiene + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Fusarium sporotrichioides
-
-
-
Trichothecium roseum
-
-
-

Reaction

Reaction Comment Organism Reaction ID
(2E,6E)-farnesyl diphosphate = trichodiene + diphosphate mechanism Trichothecium roseum
a
(2E,6E)-farnesyl diphosphate = trichodiene + diphosphate mechanism Fusarium sporotrichioides
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3R)-nerolidyl diphosphate
-
 Trichothecium roseum ?
-
 ?
(3R)-nerolidyl diphosphate
-
 Fusarium sporotrichioides ?
-
 ?
(E,E)-farnesyl diphosphate
-
 Trichothecium roseum trichodiene + diphosphate
-
 ?
(E,E)-farnesyl diphosphate
-
 Fusarium sporotrichioides trichodiene + diphosphate
-
 ?
(E,E)-farnesyl diphosphate formation of trichodiene involves initial generation of (3R)-nerolidyl diphosphate Trichothecium roseum trichodiene + diphosphate
-
 ?
(E,E)-farnesyl diphosphate formation of trichodiene involves initial generation of (3R)-nerolidyl diphosphate Fusarium sporotrichioides trichodiene + diphosphate
-
 ?
(E,E)-farnesyl diphosphate which cyclizes via the anti-boat conformation Trichothecium roseum trichodiene + diphosphate
-
 ?
additional information reaction proceeds via isomerization of farnesyl diphosphate to (3R)-nerolidyl diphosphate and further to trichodiene Trichothecium roseum ?
-
 ?