Literature summary for 4.2.3.5 extracted from

Rauch, G.; Ehammer, H.; Bornemann, S.; Macheroux, P.
Mutagenic analysis of an invariant aspartate residue in chorismate synthase supports its role as an active site base (2007), Biochemistry, 46, 3768-3774.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Neurospora crassa

Protein Variants

Protein Variants	Comment	Organism
D367A	comparable to the wild-type enzyme with respect to substrate and cofactor binding, but activity significantly lower	Neurospora crassa
D367N	comparable to the wild-type enzyme with respect to substrate and cofactor binding, but activity significantly lower	Neurospora crassa

Inhibitors

Inhibitors	Comment	Organism	Structure
dioxygen	inactivation	Neurospora crassa

Organism

Organism	UniProt	Comment	Textmining
Neurospora crassa	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-enolpyruvylshikimate 3-phosphate	-	Neurospora crassa	chorismate + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
chorismate synthase	-	Neurospora crassa

Cofactor

Cofactor	Comment	Organism	Structure
FMN	essential for catalytic activity	Neurospora crassa

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Release 2023.1 (January 2023)