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Literature summary for 4.2.3.43 extracted from

  • Toyomasu, T.; Tsukahara, M.; Kaneko, A.; Niida, R.; Mitsuhashi, W.; Dairi, T.; Kato, N.; Sassa, T.
    Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi (2007), Proc. Natl. Acad. Sci. USA, 104, 3084-3088.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.3.43

Cloned(Commentary)

Cloned (Comment) Organism
heterologous expression of PaFS alone results in the accumulation of fusicocca-2,10 (14)-diene in Escherichia coli cells Diaporthe amygdali

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geranylgeranyl diphosphate Diaporthe amygdali the enzyme contains two domains, an N-terminal terpene cyclase domain and a C-terminal prenyltransferase domain, and converts isoprene units sequentially into geranylgeranyl diphosphate and then into fusicocca-2,10 (14)-diene fusicocca-2,10(14)-diene + diphosphate
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 ?

Organism

Organism UniProt Comment Textmining
Diaporthe amygdali A2PZA5
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-

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
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 Diaporthe amygdali
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate
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 Diaporthe amygdali fusicocca-2,10(14)-diene + diphosphate
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 ?
geranylgeranyl diphosphate the enzyme contains two domains, an N-terminal terpene cyclase domain and a C-terminal prenyltransferase domain, and converts isoprene units sequentially into geranylgeranyl diphosphate and then into fusicocca-2,10 (14)-diene Diaporthe amygdali fusicocca-2,10(14)-diene + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
fusicoccadiene synthase
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 Diaporthe amygdali
PaFS
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 Diaporthe amygdali