Literature summary for 4.2.3.190 extracted from

Zerbe, P.; Hamberger, B.; Yuen, M.; Chiang, A.; Sandhu, H.; Madilao, L.; Nguyen, A.; Hamberger, B.; Bach, S.; Bohlmann, J.
Gene discovery of modular diterpene metabolism in nonmodel systems (2013), Plant Physiol., 162, 1073-1091 .

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Organism

Organism	UniProt	Comment	Textmining
Grindelia hirsutula	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate	-	Grindelia hirsutula	manoyl oxide + diphosphate	-	?
additional information	reaction proceeds via cleavage of the diphosphate group of LPP and subsequent heterocyclic ring closure including the hydroxyl group at C-8	Grindelia hirsutula	?	-	?

Synonyms

Synonyms	Comment	Organism
TPS6	-	Grindelia hirsutula

General Information

General Information	Comment	Organism
physiological function	combination of TPS6 with TPS1 in in vitro and in vivo assays results in formation of manoyl oxide with only traces of epi-manoyl oxide. TPS6 forms abietadiene when coupled with ent-CPS	Grindelia hirsutula

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Release 2023.1 (January 2023)