Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Streptomyces albus |
overexpressed in Escherichia coli | Streptomyces albus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50500 | - |
x * 50500, SDS-PAGE, His-tagged recombinant protein | Streptomyces albus |
50550 | - |
x * 50550, polyhistidine-tagged protein, SDS-PAGE | Streptomyces albus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-sedoheptulose 7-phosphate | Streptomyces albus | the enzyme is involved in biosynthesis of 2-epi-5-epi-valiolone a precursor in the biosynthesis of C7N-aminocyclitol-containing natural products, such as validamycin and acarbose | 2-epi-5-epi-valiolone + phosphate | - |
? | |
D-sedoheptulose 7-phosphate | Streptomyces albus ATCC 21838 | the enzyme is involved in biosynthesis of 2-epi-5-epi-valiolone a precursor in the biosynthesis of C7N-aminocyclitol-containing natural products, such as validamycin and acarbose | 2-epi-5-epi-valiolone + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces albus | A8D7K2 | - |
- |
Streptomyces albus ATCC 21838 | A8D7K2 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces albus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-sedoheptulose 7-phosphate | the enzyme is involved in biosynthesis of 2-epi-5-epi-valiolone a precursor in the biosynthesis of C7N-aminocyclitol-containing natural products, such as validamycin and acarbose | Streptomyces albus | 2-epi-5-epi-valiolone + phosphate | - |
? | |
D-sedoheptulose 7-phosphate | SalQ has high specificity for sedoheptulose 7-phosphate as substrate. No activity with D-glucose 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate, 3-deoxy-D-arabino-heptulosonate 7-phosphate and D-ribose 5-phosphate | Streptomyces albus | 2-epi-5-epi-valiolone + phosphate | - |
? | |
D-sedoheptulose 7-phosphate | the enzyme is involved in biosynthesis of 2-epi-5-epi-valiolone a precursor in the biosynthesis of C7N-aminocyclitol-containing natural products, such as validamycin and acarbose | Streptomyces albus ATCC 21838 | 2-epi-5-epi-valiolone + phosphate | - |
? | |
D-sedoheptulose 7-phosphate | SalQ has high specificity for sedoheptulose 7-phosphate as substrate. No activity with D-glucose 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate, 3-deoxy-D-arabino-heptulosonate 7-phosphate and D-ribose 5-phosphate | Streptomyces albus ATCC 21838 | 2-epi-5-epi-valiolone + phosphate | - |
? | |
additional information | no substrates: amino 3-deoxy-D-arabino-heptulosonate 7-phosphate, 3-deoxy-D-arabino-heptulosonate 7-phosphate, glucose 6-phosphate, fructose 6-phosphate, mannose 6-phosphate, and ribose 5-phosphate | Streptomyces albus | ? | - |
? | |
additional information | no substrates: amino 3-deoxy-D-arabino-heptulosonate 7-phosphate, 3-deoxy-D-arabino-heptulosonate 7-phosphate, glucose 6-phosphate, fructose 6-phosphate, mannose 6-phosphate, and ribose 5-phosphate | Streptomyces albus ATCC 21838 | ? | - |
? | |
sedoheptulose 7-phosphate | - |
Streptomyces albus | 2-epi-5-epi-valiolone + phosphate | - |
? | |
sedoheptulose 7-phosphate | - |
Streptomyces albus ATCC 21838 | 2-epi-5-epi-valiolone + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50550, polyhistidine-tagged protein, SDS-PAGE | Streptomyces albus |
? | x * 50500, SDS-PAGE, His-tagged recombinant protein | Streptomyces albus |
Synonyms | Comment | Organism |
---|---|---|
SalQ | - |
Streptomyces albus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Streptomyces albus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Streptomyces albus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in biosynthesis of 2-epi-5-epi-valiolone a precursor in the biosynthesis of C7N-aminocyclitol-containing natural products, such as validamycin and acarbose | Streptomyces albus |