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Literature summary for 4.2.3.145 extracted from

  • Chiba, R.; Minami, A.; Gomi, K.; Oikawa, H.
    Identification of ophiobolin F synthase by a genome mining approach: a sesterterpene synthase from Aspergillus clavatus (2013), Org. Lett., 15, 594-597.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Aspergillus clavatus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ used in assay conditions Aspergillus clavatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O Aspergillus clavatus
-
 ophiobolin F + diphosphate
-
 ?
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O Aspergillus clavatus NRRL 1
-
 ophiobolin F + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus clavatus
-
-
-
Aspergillus clavatus NRRL 1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Aspergillus clavatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O
-
 Aspergillus clavatus ophiobolin F + diphosphate
-
 ?
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O
-
 Aspergillus clavatus NRRL 1 ophiobolin F + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
ACLA_76850
-
 Aspergillus clavatus