Literature summary for 4.2.3.133 extracted from

Xie, X.; Kirby, J.; Keasling, J.D.
Functional characterization of four sesquiterpene synthases from Ricinus communis (castor bean) (2012), Phytochemistry, 78, 20-28.

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Application

Application	Comment	Organism
synthesis	expression in Saccharomyces cerevisiae leads to a titer of (-)-alpha-copaene of 9 mg/l at 48 h and around 7 mg/l in Escherichia coli, and the titer of (+)-delta-cadinene is 6 mg/l in Saccharomyces cerevisiae and 3.5 mg/l in Escherichia coli	Ricinus communis

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Saccharomyces cerevisiae strain EPY300	Ricinus communis
exprsssion in Escherichia coli and Saccharomyces cerevisiae	Ricinus communis

Organism

Organism	UniProt	Comment	Textmining
Ricinus communis	B9S9Z3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Ricinus communis	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2E,6E)-farnesyl diphosphate	-	Ricinus communis	(+)-delta-cadinene + diphosphate	yield of 40% (+)-delta-cadinene	?
(2E,6E)-farnesyl diphosphate	-	Ricinus communis	(-)-alpha-copaene + diphosphate	yield of 60% (-)-alpha-copaene	?
(2E,6E)-farnesyl diphosphate	-	Ricinus communis	(-)-alpha-copaene + diphosphate	products are about 60% (-)-alpha-copaene, 40% (+)-delta-cadinene	?

Synonyms

Synonyms	Comment	Organism
sesquiterpene synthase 1	-	Ricinus communis
SeTPS1	-	Ricinus communis
TPS1	-	Ricinus communis

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Release 2023.1 (January 2023)