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Literature summary for 4.2.3.12 extracted from

  • Pribat, A.; Jeanguenin, L.; Lara-Nunez, A.; Ziemak, M.J.; Hyde, J.E.; de Crecy-Lagard, V.; Hanson, A.D.
    6-Pyruvoyltetrahydropterin synthase paralogs replace the folate synthesis enzyme dihydroneopterin aldolase in diverse bacteria (2009), J. Bacteriol., 191, 4158-4165.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
His-tagged version expressed in Escherichia coli BL21(DE3) Clostridium botulinum
His-tagged version expressed in Escherichia coli BL21(DE3) Leptospira interrogans

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
 Clostridium botulinum
Zn2+
-
 Leptospira interrogans

Organism

Organism UniProt Comment Textmining
Clostridium botulinum
-
-
-
Leptospira interrogans
-
-
-

Purification (Commentary)

Purification (Comment) Organism
immobilized metal ion affinity chromatography (Ni2+) Clostridium botulinum
immobilized metal ion affinity chromatography (Ni2+) Leptospira interrogans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydroneopterin triphosphate
-
 Clostridium botulinum 6-hydroxymethyldihydropterin + triphosphate + ?
-
 ?
dihydroneopterin triphosphate
-
 Leptospira interrogans 6-hydroxymethyldihydropterin + triphosphate + ?
-
 ?

Synonyms

Synonyms Comment Organism
6-pyruvoyltetrahydropterin synthase paralog
-
 Clostridium botulinum
6-pyruvoyltetrahydropterin synthase paralog
-
 Leptospira interrogans
6-pyruvoyltetrahydropterin synthase-like protein
-
 Clostridium botulinum
6-pyruvoyltetrahydropterin synthase-like protein
-
 Leptospira interrogans
PTPS-III
-
 Clostridium botulinum
PTPS-III
-
 Leptospira interrogans