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Literature summary for 4.2.2.8 extracted from

  • Prinz, R.; Klein, U.; Sudhakaran, P.R.; Sinn, W.; Ullrich, K.; von Figura, K.
    Metabolism of sulfated glycosaminoglycans in rat hepatocytes. Synthesis of heparan sulfate and distribution into cellular and extracellular pools (1980), Biochim. Biophys. Acta, 630, 402-413.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
heparan sulfate Rattus norvegicus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heparan sulfate
-
 Rattus norvegicus non-sulfated di- and tetrasaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends + SO42-
-
 ?
heparan sulfate
-
 Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
 activity higher at 5.5 than at 4.5 Rattus norvegicus