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Literature summary for 4.2.2.5 extracted from
- The synthesis of a novel thio-linked disaccharide of chondroitin as a potential inhibitor of polysaccharide lyases (2004), Carbohydr. Res., 339, 699-703.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| benzyl S-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)-(1-4)-4-deoxy-4-thio-beta-D-glucopyranosiduronic acid | competitive versus phenyl 4-O -(2',4'-dinitrophenyl)-beta-D-glucopyranosiduronic acid | Pedobacter heparinus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pedobacter heparinus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyl S-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)-(1-4)-4-deoxy-4-thio-beta-D-glucopyranosiduronic acid | very slow cleavage, 9% product after 24 h | Pedobacter heparinus | ? | - |
? | |
| phenyl 4-O-(2',4'-dinitrophenyl)-beta-D-glucopyranosiduronic acid | - |
Pedobacter heparinus | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.005 | - |
benzyl S-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)-(1-4)-4-deoxy-4-thio-beta-D-glucopyranosiduronic acid | - |
Pedobacter heparinus | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 45 | - |
benzyl S-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)-(1-4)-4-deoxy-4-thio-beta-D-glucopyranosiduronic acid | - |
Pedobacter heparinus | |
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