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Literature summary for 4.2.2.3 extracted from
- Alginate lyase enhances antibiotic killing of mucoid Pseudomonas aeruginosa in biofilms (2006), Apmis, 114, 131-138.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | once mucoid strains of Pseudomonas aeruginosa have become established in the respiratory tracts of cystic fibrosis patients they can rarely be eliminated by antibiotic treatment alone. Coadministration of antibiotics with alginate lyase, which degrades the exopolysaccharide produced by mucoid strains of pseudomonas aeruginosa might benefit cystic fibrosis patients by increasing the efficacy of antibioticin the respiratory tract | Pseudomonas aeruginosa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
mucoid strains FRD1 and 144M from the lungs of patients with cystic fibrosis | - |
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Release 2023.1 (January 2023)
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