Any feedback?
Literature summary for 4.2.2.20 extracted from
- Chondroitinase ABC improves basic and skilled locomotion in spinal cord injured cats (2008), Exp. Neurol., 209, 483-496.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | effects of degrading chondroitin sulfate glycosaminoglycan with Ch'ase ABC in the injured spinal cords of adult cats is assessed. Recovery of skilled locomotion (ladder, peg, and beam) is significantly accelerated in Ch'ase ABC-treated cats compared to controls. Ch'ase ABC-treated cats also show greater recovery of specific skilled locomotor features including intralimb movement patterns and significantly greater paw placement onto pegs. These findings show that intraspinal cleavage of CS GAGs can enhance recovery of function following spinal cord injury in large animals with sophisticated motor behaviors and axonal growth requirements similar to those encountered in humans | Proteus vulgaris |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Proteus vulgaris | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ch'ase ABC | - |
Proteus vulgaris |
| chondroitinase ABC | - |
Proteus vulgaris |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
