Any feedback?
Literature summary for 4.2.2.11 extracted from
- Alginate lyase: review of major sources and enzyme characteristics, structure-function analysis, biological roles, and applications (2000), Annu. Rev. Microbiol., 54, 289-340.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Vibrio harveyi | - |
- |
| extracellular | - |
Corynebacterium sp. | - |
- |
| extracellular | - |
Klebsiella pneumoniae | - |
- |
| extracellular | - |
Vibrio sp. | - |
- |
| extracellular | - |
Pseudoalteromonas elyakovii | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Enterobacter cloacae |  |
| Ca2+ | - |
Pseudomonas sp. | |
| Ca2+ | - |
Corynebacterium sp. | |
| Ca2+ | - |
Klebsiella pneumoniae | |
| K+ | - |
Pseudoalteromonas elyakovii | |
| Mg2+ | - |
Enterobacter cloacae | |
| Mg2+ | - |
Corynebacterium sp. | |
| Mg2+ | - |
Pseudoalteromonas elyakovii | |
| Mn2+ | - |
Corynebacterium sp. | |
| Na+ | - |
Klebsiella pneumoniae | |
| Na+ | - |
Pseudoalteromonas elyakovii | |
| Na+ | 0,3-1 M optimum concentration | Vibrio harveyi | |
| Ni2+ | - |
Corynebacterium sp. | |
| Zn2+ | - |
Corynebacterium sp. | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 28600 | - |
- |
Corynebacterium sp. |
| 32000 | - |
- |
Enterobacter cloacae |
| 32000 | - |
- |
Pseudoalteromonas elyakovii |
| 38000 | - |
- |
Sargassum sp. |
| 40000 | 42000 | - |
Vibrio sp. |
| 57000 | - |
- |
Vibrio harveyi |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| poly-alpha-L-guluronic acid | Vibrio harveyi | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Corynebacterium sp. | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Klebsiella pneumoniae | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Bacillus sp. (in: Bacteria) | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Vibrio sp. | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Sphingobacterium multivorum | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Sargassum sp. | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Pseudoalteromonas elyakovii | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | Vibrio harveyi AL-128 | - |
unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus sp. (in: Bacteria) | - |
- |
- |
| Corynebacterium sp. | - |
- |
- |
| Corynebacterium sp. | Q9RB42 | - |
- |
| Enterobacter cloacae | - |
- |
- |
| Klebsiella pneumoniae | - |
- |
- |
| Pseudoalteromonas elyakovii | Q9Z6D6 | extracellular isozyme; several isozymes with homo- or heterogenous substrate specificities | - |
| Pseudomonas aeruginosa | - |
- |
- |
| Pseudomonas sp. | - |
- |
- |
| Sargassum sp. | - |
- |
- |
| Sphingobacterium multivorum | - |
- |
- |
| Vibrio harveyi | - |
AL-128 | - |
| Vibrio harveyi AL-128 | - |
AL-128 | - |
| Vibrio sp. | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha-L-guluronosyl linkage in alginate | - |
Klebsiella pneumoniae | ? | - |
? | |
| alpha-L-guluronosyl linkage in alginate | endolyase | Enterobacter cloacae | ? | - |
? | |
| alpha-L-guluronosyl linkage in alginate | endolyase | Corynebacterium sp. | ? | - |
? | |
| alpha-L-guluronosyl linkage in alginate | endolyase | Sphingobacterium multivorum | ? | - |
? | |
| alpha-L-guluronosyl linkage in alginate | endolyase | Pseudoalteromonas elyakovii | ? | - |
? | |
| additional information | - |
Corynebacterium sp. | ? | - |
? | |
| additional information | nine amino acid block conserved in the N-terminus | Klebsiella pneumoniae | ? | - |
? | |
| additional information | nine amino acid block conserved in the N-terminus | Corynebacterium sp. | ? | - |
? | |
| additional information | nine amino acid conserved block at the C-termini, unrelated to substrate recognition but to maintenance of the stable three-dimensional conformation | Corynebacterium sp. | ? | - |
? | |
| additional information | nine amino acid conserved block at the C-termini, unrelated to substrate recognition but to maintenance of the stable three-dimensional conformation | Pseudoalteromonas elyakovii | ? | - |
? | |
| additional information | exolytic and endolytic activity | Sargassum sp. | ? | - |
? | |
| additional information | the first twenty amino acids are completely identical in Klebsiella pneumoniae and in Enterobacter cloacae, N-terminus | Enterobacter cloacae | ? | - |
? | |
| additional information | the first twenty amino acids are completely identical in Klebsiella pneumoniae and in Enterobacter cloacae, N-terminus | Klebsiella pneumoniae | ? | - |
? | |
| additional information | L-tryptophan, L-histidine and L-lysine residues play an important role in enzymatic activity | Klebsiella pneumoniae | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Vibrio harveyi | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Corynebacterium sp. | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Klebsiella pneumoniae | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Bacillus sp. (in: Bacteria) | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Vibrio sp. | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Sphingobacterium multivorum | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Sargassum sp. | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Pseudoalteromonas elyakovii | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Vibrio harveyi AL-128 | ? | - |
? | |
| poly-alpha-L-guluronic acid | - |
Vibrio harveyi | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Corynebacterium sp. | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Klebsiella pneumoniae | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Bacillus sp. (in: Bacteria) | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Vibrio sp. | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Sphingobacterium multivorum | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Sargassum sp. | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Pseudoalteromonas elyakovii | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-alpha-L-guluronic acid | - |
Vibrio harveyi AL-128 | unsaturated 1,4-di-, 1,4-tri- and 1,4-tetrasaccharides of L-guluronate | - |
? | |
| poly-beta1,4-D-mannuronan | - |
Enterobacter cloacae | ? | - |
? | |
| poly-beta1,4-D-mannuronan | - |
Bacillus sp. (in: Bacteria) | ? | - |
? | |
| poly-beta1,4-D-mannuronan | - |
Pseudoalteromonas elyakovii | ? | - |
? | |
| saturated hexa((1-4)-alpha-L-guluronan) | rapidly degraded in the endolytic mode, enzyme has a subsite corresponding to hexa((1-4)-alpha-L-guluronan) units, cleaving the substrate between subsites two and three from the non-reducing end | Corynebacterium sp. | unsaturated tetramer and a saturated dimer | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
- |
Pseudoalteromonas elyakovii |
| 30 | - |
extracellular enzyme | Enterobacter cloacae |
| 40 | - |
- |
Sphingobacterium multivorum |
| 40 | - |
intracellular enzyme | Enterobacter cloacae |
| 45 | - |
- |
Vibrio sp. |
| 50 | - |
- |
Klebsiella pneumoniae |
| 55 | - |
- |
Corynebacterium sp. |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Corynebacterium sp. |
| 7.5 | - |
- |
Pseudomonas sp. |
| 7.5 | - |
- |
Bacillus sp. (in: Bacteria) |
| 7.5 | - |
- |
Pseudoalteromonas elyakovii |
| 7.5 | - |
intracellular enzyme | Enterobacter cloacae |
| 7.6 | - |
- |
Klebsiella pneumoniae |
| 7.8 | - |
- |
Vibrio harveyi |
| 7.8 | - |
extracellular enzyme | Enterobacter cloacae |
| 8.5 | - |
- |
Vibrio sp. |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Vibrio harveyi | - |
4.4 | 4.3 |
| Sargassum sp. | - |
- |
4.5 |
| Pseudoalteromonas elyakovii | - |
4.8 | 4.7 |
| Corynebacterium sp. | - |
7.4 | 7.3 |
| Enterobacter cloacae | - |
- |
8.9 |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
