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Literature summary for 4.2.1.92 extracted from
- Jasmonate biochemical pathway (2010), Sci. Signal., 109, 1-6.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| F137L | site-directed mutagenesis, mutation of this residue to Leu results in the enzyme having hydroperoxide lyase activity | Arabidopsis thaliana |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Arabidopsis thaliana | 9507 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 58000 | - |
x * 58000 | Arabidopsis thaliana |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | Q96242 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Arabidopsis thaliana | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 58000 | Arabidopsis thaliana |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| allene oxide synthase | - |
Arabidopsis thaliana |
| AOS | belongs to the CYP74 family | Arabidopsis thaliana |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | AOS is involved in the jasmonate biochemical pathway, detailed overview | Arabidopsis thaliana |
| physiological function | the lipoxygenase-catalyzed addition of molecular oxygen to alpha-linolenic acid initiates jasmonate synthesis by providing a 13-hydroperoxide substrate for formation of an unstable allene oxide by allene oxide synthase. This allene oxide then undergoes enzyme-guided cyclization to produce 12-oxophytodienoic acid. Phe137 stabilizes the carbon-centered radical intermediate, which is essential for AOS activity | Arabidopsis thaliana |
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Release 2023.1 (January 2023)
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