Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | exhibits weak activity prior to activation (in vitro), can be massively activated with detergent | Arabidopsis thaliana |
Cloned (Comment) | Organism |
---|---|
- |
Parthenium argentatum |
Crystallization (Comment) | Organism |
---|---|
- |
Arabidopsis thaliana |
is a typical P450, the loop forms a compact beta-turn and incorporates the most typical P450 consensus sequence, FXXG, followed by three residues (XRX) followed by CXG encompassing the cysteine. CYP74 heme is strongly hold in place than usual via ionic interactions with its proprionate groups | Parthenium argentatum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
heme | CYP74 heme is strongly hold in place than usual via ionic interactions with its proprionate groups | Parthenium argentatum | |
Iron | - |
Arabidopsis thaliana |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
53000 | - |
- |
Parthenium argentatum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acaryochloris marina | - |
- |
- |
Arabidopsis thaliana | - |
- |
- |
Linum usitatissimum | - |
seed | - |
Parthenium argentatum | - |
- |
- |
Solanum lycopersicum | - |
- |
- |
Solanum tuberosum | - |
- |
- |
Zea mays | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Linum usitatissimum |
- |
Parthenium argentatum |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | CYP74A2 is most abundant in rubber, accounting for about 50% of the protein content | Parthenium argentatum | - |
seed | - |
Linum usitatissimum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CYP74 enzymes use their fatty acid hydroperoxide substrate to activate the enzyme and substrate in one and the same step | Linum usitatissimum | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
allene oxide synthase | - |
Zea mays |
allene oxide synthase | - |
Solanum tuberosum |
allene oxide synthase | - |
Arabidopsis thaliana |
allene oxide synthase | - |
Solanum lycopersicum |
allene oxide synthase | - |
Linum usitatissimum |
allene oxide synthase | - |
Parthenium argentatum |
allene oxide synthase | - |
Acaryochloris marina |
AOS | - |
Zea mays |
AOS | - |
Solanum tuberosum |
AOS | - |
Arabidopsis thaliana |
AOS | - |
Solanum lycopersicum |
AOS | - |
Linum usitatissimum |
AOS | - |
Parthenium argentatum |
AOS | - |
Acaryochloris marina |
CYP74 | - |
Linum usitatissimum |
CYP741 | - |
Arabidopsis thaliana |
CYP742 | - |
Parthenium argentatum |
CYP74A | - |
Zea mays |
CYP74c | - |
Solanum tuberosum |
CYP74c | - |
Solanum lycopersicum |
General Information | Comment | Organism |
---|---|---|
metabolism | role for Phe137 in catalysis, mutation to Leu switches the product outcome from AOS to hydroperoxide lyase | Arabidopsis thaliana |
physiological function | is a cytochrome P450 | Linum usitatissimum |
physiological function | is a potential rubber transferase, the enzyme polymerizes thousands of isoprenes into molecules of rubber. Plays no role in jasmonate biosynthesis | Parthenium argentatum |
physiological function | plays a role in jasmonate biosynthesis | Zea mays |
physiological function | plays a role in jasmonate biosynthesis | Solanum tuberosum |
physiological function | plays a role in jasmonate biosynthesis | Solanum lycopersicum |