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Literature summary for 4.2.1.91 extracted from

  • Yamada, T.; Matsuda, F.; Kasai, K.; Fukuoka, S.; Kitamura, K.; Tozawa, Y.; Miyagawa, H.; Wakasa, K.
    Mutation of a rice gene encoding a phenylalanine biosynthetic enzyme results in accumulation of phenylalanine and tryptophan (2008), Plant Cell, 20, 1316-1329.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.91

Cloned(Commentary)

Cloned (Comment) Organism
-
 Oryza sativa

Protein Variants

Protein Variants Comment Organism
S298I mutant Mtr1 Oryza sativa

Inhibitors

Inhibitors Comment Organism Structure
L-phenylalanine
-
 Oryza sativa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.12
-
 arogenate wild-type, rice ADT is a bifunctional enzyme Oryza sativa
0.17
-
 arogenate mutant S298I, rice ADT is a bifunctional enzyme Oryza sativa

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
 Oryza sativa 9507
-

Organism

Organism UniProt Comment Textmining
Oryza sativa A8CF65 Oryza sativa subsp. japonica (Rice)
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arogenate bifunctional enzyme, PDT activity with prephenate and ADT activity with arogenate Oryza sativa L-phenylalanine + H2O + CO2
-
 ?

Synonyms

Synonyms Comment Organism
AdT bifunctional enzyme, PDT activity with prephenate and ADT activity with arogenate Oryza sativa
arogenate dehydratase bifunctional enzyme, PDT activity with prephenate and ADT activity with arogenate Oryza sativa

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
7.36
-
 L-phenylalanine wild-type, rice ADT is a bifunctional enzyme Oryza sativa
61.5
-
 L-phenylalanine mutant enzyme S298I, rice ADT is a bifunctional enzyme Oryza sativa

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
 L-phenylalanine more than 0.5 Oryza sativa additional information
0.016
-
 wild-type, rice ADT is a bifunctional enzyme Oryza sativa L-phenylalanine