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Literature summary for 4.2.1.84 extracted from

  • Taniguchi, K.; Murata, K.; Murakami, Y.; Takahashi, S.; Nakamura, T.; Hashimoto, K.; Koshino, H.; Dohmae, N.; Yohda, M.; Hirose, T.; Maeda, M.; Odaka, M.
    Novel catalytic activity of nitrile hydratase from Rhodococcus sp. N771 (2008), J. Biosci. Bioeng., 106, 174-179.
    View publication on PubMed
Search for more literature for 4.2.1.84

Inhibitors

Inhibitors Comment Organism Structure
tert-butylisonitrile substrate inhibition, a Dixon plot shows the reciprocal values of the rate of methacrylonitrile hydration as a function of tert-butylisonitrile concentration, overview Rhodococcus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rhodococcus sp. NHase is a non-heme iron enzyme catalyzing the hydration of various nitriles to the corresponding amides ?
-
 ?
additional information Rhodococcus sp. N771 NHase is a non-heme iron enzyme catalyzing the hydration of various nitriles to the corresponding amides ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rhodococcus sp.
-
-
-
Rhodococcus sp. N771
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,1,3,3,-tetramethylbutylisonitrile + H2O
-
 Rhodococcus sp. 1,1,3,3,-tetramethylisobutylamide
-
 ?
1,1,3,3,-tetramethylbutylisonitrile + H2O
-
 Rhodococcus sp. N771 1,1,3,3,-tetramethylisobutylamide
-
 ?
isovaleronitrile + H2O
-
 Rhodococcus sp. isovaleric acid amide product identification by liquid chromatography tandem mass spectrometry ?
isovaleronitrile + H2O
-
 Rhodococcus sp. N771 isovaleric acid amide product identification by liquid chromatography tandem mass spectrometry ?
methacrylonitrile + H2O low activity Rhodococcus sp. methacrylamide
-
 ?
methacrylonitrile + H2O low activity Rhodococcus sp. N771 methacrylamide
-
 ?
additional information NHase is a non-heme iron enzyme catalyzing the hydration of various nitriles to the corresponding amides Rhodococcus sp. ?
-
 ?
additional information NHase is a non-heme iron enzyme catalyzing the hydration of various nitriles to the corresponding amides Rhodococcus sp. N771 ?
-
 ?
tert-butylisonitrile + H2O
-
 Rhodococcus sp. tert-butyl amide
-
 ?
tert-butylisonitrile + H2O
-
 Rhodococcus sp. N771 tert-butyl amide
-
 ?

Synonyms

Synonyms Comment Organism
NHase
-
 Rhodococcus sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Rhodococcus sp.