Literature summary for 4.2.1.51 extracted from

Vivan, A.L.; Caceres, R.A.; Abrego, J.R.; Borges, J.C.; Ruggiero Neto, J.; Ramos, C.H.; de Azevedo, W.F.; Basso, L.A.; Santos, D.S.
Structural studies of prephenate dehydratase from Mycobacterium tuberculosis H37Rv by SAXS, ultracentrifugation, and computational analysis (2008), Proteins, 72, 1352-1362.

Search for more literature for 4.2.1.51

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3), pET-23a(+) expression vector	Mycobacterium tuberculosis

Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Mycobacterium tuberculosis

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
125000	-	predicted by dynamic light scattering	Mycobacterium tuberculosis
134500	-	predicted as a tetrameric globular particle	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	P9WIC3	encoded by pheA gene (Rv3838c); H37Rv	-
Mycobacterium tuberculosis H37Rv	P9WIC3	encoded by pheA gene (Rv3838c); H37Rv	-

Purification (Commentary)

Purification (Comment)	Organism
gel filtration, recombinant protein	Mycobacterium tuberculosis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	three-dimensional enzyme structure, oligomeric state determined, circular dichroism method and bioinformatics tools, hydrodynamic properties, analytical ultracentrifugation experiments, small angle X-ray scattering, enzyme stability shown by molecular dynamics simulations, predicted as a flat disk protein with an asymmetric shape	Mycobacterium tuberculosis

Subunits

Subunits	Comment	Organism
homotetramer	determined by small angle X-ray scattering and analytical ultracentrifugation	Mycobacterium tuberculosis

Synonyms

Synonyms	Comment	Organism
MtbPDT	-	Mycobacterium tuberculosis

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Release 2023.1 (January 2023)